The relationship anywhere between diet, times equilibrium and fertility in the men

The relationship anywhere between diet, times equilibrium and fertility in the men

Abstract. Research conducted in recent years provides more and more evidence that diet can have a significant impact on male fertility. The aim of the study was to analyze the relationship between diet, energy balance and fertility in men. A comprehensive literature search of published studies in various languages, was carried out in electronic databases. The direct analysis included 96 works published between 2008 and 2018, including 12 randomized controlled trials and 23 systematic reviews and meta-analyses. A strong adherence to a healthy dietary pattern is positively correlated with total sperm count, progressive motility and total motile sperm count (all p < 0.05). However, attention is drawn to the fact that foods that are considered “healthy” can sometimes contain a significant amount of pollution, which negatively affect the semen parameters. An adequate intake of antioxidants or their supplementation have been quite effective in the prevention and treatment of male infertility. The improvement of pregnancy rate after antioxidant therapy ranged in various studies from 11% to 41%. An important problem, however, may be choosing the right dose of the supplement or finding an appropriate combination of antioxidants that may be more effective than any single antioxidant. The normalization of men's body weight is beneficial for the quality of sperm and the concentration of male reproductive hormones. Further, long-term studies require the assessment of the impact of drastic weight loss after bariatric surgery on male fertility.


The fresh incidence regarding infertility certainly one of people regarding reproductive age brackets, according to certain present, regarding 8% to twenty five% [1–3]. Men sterility is the merely reason behind sterility inside 20–30% out of instances and you can something leading to sterility inside fifty% of all of the sterility instances . New assessment regarding male fertility always has medical examination and comparison toward reference philosophy of one’s adopting the semen parameters: volume, complete sperm fertility, attention, motility and you will morphology (Desk step 1) . Reduced sperm fertility and/or quality can be acquired inside 90% regarding partners that have virility troubles . From the testing of virility, this new levels of male reproductive hormones are also analyzed. More recently, the brand new molecular constitution of spunk tissues, examined of the evaluating the degree of DNA fragmentation otherwise oxidative be concerned could have been much more taken into account. Several degree make use of the DNA fragmentation index (DFI) while the a sign of pregnancy triumph. According to Evenson and you will Wixon, DFI ranges out-of less than six% in the fit men, when you are an effective DFI away from ? 30% was for the faster virility . Currently laid out hereditary activities, and one another chromosomal aberrations and monogenic changes, make up just about ten–15% out of cases of male infertility . The source getting virility troubles can be environmental affairs. The purpose of the research would be to get acquainted with the connection between eating plan, times balance and you can virility prices in males.

Method from literature search

A comprehensive literature search of published studies in various languages, was carried out in electronic databases, including: PubMed, Cochrane Central Register of Controlled Trials (CENTRAL), Cochrane Database of Systematic Review and Google Scholar. Randomized controlled trials, observational and qualitative studies published between 2008 and 2018 (up to and including March) were included. The following keywords related to male infertility, diet, nutrients and their combinations (made by applying operators AND and OR) were used in the search: ‘male infertility’, ‘sperm quality’, ‘idiopathic oligozoospermia’, ‘astenoazospermia’, ‘oligoastenoteratozoospermia’, ‘sperm DNA damage’, ‘nutritional status’, ‘BMI’, ‘obesity’, ‘diet’, ‘nutrition’, dietary pattern’, ‘food’, ‘nutrient’, ‘fatty acids’, ‘antioxidant’, ‘supplementation’, ‘vitamin C’, ‘vitamin E’,’ vitamin A’, ‘folate’, ‘zinc’, ‘selenium’, ‘L-carnitine’, ‘glutathione’, ‘coenzyme Q10‘, ‘N-acetylcysteine’, ‘lycopene’. Reference lists of studies extracted from the primary electronic search were used to identify additional relevant studies.

Sperm factor Reference limit (95% confidence times)
Sperm volume 1.5 ml (1.4–step one.7)
Total sperm fertility 39 million per squirt (33–46)
Cum focus 15 mil each ml (12–16)
Vitality 58% real time (55–63)
Modern motility 32% (31–34)
Total (progressive + nonprogressive) motility 40% (38–42)
Morphologically normal forms cuatro.0% (step 3.0–cuatro.0)